Interventional Magnetic Resonance Imaging
David Saloner, PhD, Director

Research Directions:

• Evaluation of benefit added by using MRI in combination with an interventional angiography suite
• Development of real-time MRI methods for guiding interventions in the MRI scanner
• Assessing the use of MR-determined hemodynamic measures for monitoring interventional procedures such as stenting or angioplasty
• Determination of changes in end-organ perfusion in response to interventional procedures
• Development of methods for site-specific delivery of therapeutic agents
• Development of MR guided cardiac catheterization
• Evaluation of MR monitoring of tumor embolization therapy
• MR guidance of Deep Brain Stimulator placement

Recent Key References:

Saeed M, Weber O, Lee R, Do L, Martin A, Saloner D, Ursell P, Robert P, Corot C, Higgins CB. Discrimination of myocardial acute and chronic (scar) infarctions on delayed contrast enhanced magnetic resonance imaging with intravascular magnetic resonance contrast media. J Am Coll Cardiol. 2006; 48(10): 1961-8.

Acevedo-Bolton G, Jou LD, Dispensa BP, Lawton MT, Higashida RT, Martin AJ, Young WL, Saloner D. Estimating the hemodynamic impact of interventional treatments of aneurysms: Numerical simulation with experimental validation: Technical case report. Neurosurgery. 2006;59:E429-430; author reply E429-430.

Saeed M, Martin AJ, Lee RJ, Weber O, Revel D, Saloner D, Higgins CB. MR Guidance of Targeted Injections into Border and Core of Scarred Myocardium in Pigs. Radiology 2006 240(2): 419-26.

Saeed M, Henk CB, Weber O, Martin A, Wilson M, Shunk K, Saloner D, Higgins CB. Delivery and assessment of endovascular stents to repair aortic coarctation using MR and X-ray imaging. J Magn Reson Imaging 2006, 24(2): 371-8.

Saloner D, Acevedo-Bolton G, Rayz V, Wintermark M, Martin A, Dispensa B, Young W, Lawton M, Rapp J, and Jou, L-D. Imaging and CFD in the analysis of vascular disease progression Proc. SPIE 2006, 6143, 144-153.

Saeed M, Lee RJ, Weber O, Do L, Martin A, Ursell P, Saloner D, Higgins CB. Scarred myocardium imposes additional burden on remote viable myocardium despite a reduction in the extent of area with late contrast MR enhancement. Eur Radiol. 2006;16(4):827-36.

Martin AJ, Larson PS, Ostrem JL, Sootsman WK, Talke P, Weber OM, Levesque N, Myers J, Starr PA. Placement of deep brain stimulator electrodes using real-time high field interventional MRI. Magn Reson Med, 2005; 54: 1107 - 1114.

Henk CB, Higgins CB, Saeed M. Endovascular interventional MRI. J Magn Reson Imaging. 2005 Oct;22(4):451-60.

Ko NU, Achrol AS, Martin AJ, Chopra M, Saloner DA, Higashida RT, Young WL. Magnetic Resonance Perfusion Tracks 133Xe Cerebral Blood Flow Changes after Carotid Stenting. Stroke, 2005; 36(3): 676-678.

Saeed M, Lee R, Martin AJ, Weber OM, Krombach G, Schalla S, Lee M, Saloner D, Higgins CB. MRI in Guiding and Assessing Intramyocardial Therapy. European Radiology 2005; 15(5):851-63).