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Upcoming Presentations - All
| Date/Time | Presentation/Lecture | Type | Location |
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14 May,2008
2-3:30PM | MEG imaging of dynamic cortical-cortical interactions: developing brain biomarkers of cognitive function in health and disease
Functional imaging studies with PET and fMRI have clearly demonstrated that multiple cortical regions are involved in cognitive operations, and growing evidence supports the notion that these cortical regions may be functionally interactive during cognition. MEG/EEG provides cortical electrophysiological measures with millisecond temporal resolution that makes it possible to investigate the interactions of cortical regions on a timescale commensurate with sub-second cognitive processes. In addition, MEG/EEG can measure oscillatory activity in different frequency bands associate with different cortical functions. These oscillatory bands therefore provide functional tags for cortical activity. I will discuss new MEG/EEG cortical imaging capabilities for: (1) imaging cortical activity in space, time and frequency; (2) investigating the sub-second dynamics of cortical-cortical interactions in different frequencies; (3) using Granger Causality measures of directional influences to investigate basic concepts of functional organization such as top-down versus bottom-up interactions in cortical networks; (4) deriving within-subject statistics for these measures, which enables studies of individual differences, effects of experience and training within individual subjects, and a wide range of clinical applications. I will provide examples of these capabilities from studies of visual and auditory attention. A major theme of this talk and discussion will be to illustrate how our results support the development of new biomarkers for cognition in health and disease.
Greg Simpson, Ph.D.
Director, Dynamic Neuroimaging Laboratory
UCSF
Contact: natalie.bareis@ucsf.edu | Seminar |
VAMC
Building 13 Conference room |
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